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Indications and Usage for Oxycodone

 

Oxycodone hydrochloride tablets are an opioid agonist indicated for the management of pain severe enough to require an opioid

analgesic and for which alternative treatments are inadequate. (1)

 

Limitations of Use:

 

Because of the risks of addiction, abuse, and misuse with opioids, which can occur at any dosage or duration, reserve oxycodone

hydrochloride tablets for use in patients for whom alternative treatment options (e.g., non-opioid analgesics or non-opioid

 

combination products):

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Have not been tolerated or are not expected to be tolerated,

Have not provided adequate analgesia or are not expected to provide adequate analgesia.

Oxycodone hydrochloride tablets should not be used for an extended period of time unless the pain remains severe enough to require

an opioid analgesic and for which alternative treatment options continue to be inadequate.

 

Oxycodone Dosage and Administration

 

Oxycodone hydrochloride tablets should be prescribed only by healthcare professionals who are knowledgeable about the use of

opioids and how to mitigate the associated risks.

 

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Use the lowest effective dosage for the shortest duration of time consistent with individual patient treatment goals. Reserve titration to

higher doses of oxycodone hydrochloride tablets for patients in whom lower doses are insufficiently effective and in whom the

expected benefits of using a higher dose opioid clearly outweigh the substantial risks. (2.1, 5)

 

Many acute pain conditions (e.g., the pain that occurs with a number of surgical procedures or acute musculoskeletal injuries) require

no more than a few days of an opioid analgesic. Clinical guidelines on opioid prescribing for some acute pain conditions are available.